Prognostic value of human papillomavirus types 16 and 18 DNA physical status in cervical intraepithelial neoplasia
نویسندگان
چکیده
منابع مشابه
Risk for high-grade cervical intraepithelial neoplasia associated with variants of human papillomavirus types 16 and 18.
BACKGROUND Although the variant lineages of human papillomavirus (HPV) types 16 and 18 are well established, their individual associations with high-grade cervical intraepithelial neoplasia (CIN) have not been extensively evaluated. METHODS Study subjects were women participating in the Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion Triage Study...
متن کاملPresence of human papillomavirus DNA sequences in cervical intraepithelial neoplasia.
Twenty two patients referred to a district colposcopy clinic because of an abnormal cervical cytology report or a suspicious cervix and found to have a cervical epithelial abnormality were studied. The techniques of cytology, histology, immunohistochemistry, and DNA-DNA hybridisation were used to detect infection by human papillomavirus. Using an indirect immunoalkaline phosphatase technique hu...
متن کاملAnalysis of the physical state of human papillomavirus type-16 in early cervical intraepithelial neoplasia.
Cervical cancer is one of the most common malignant diseases in women world-wide. Infection with certain types of Human Papillomavirus (HPV) in particular HPV-16 and other related types (HPV-18, -31 and -33 ) appears to be an important etiologic factor in the development of cervical intraepithelial neoplasia (CIN) and cervical carcinoma. HPV infections causing clinically apparent lesions of the...
متن کاملHuman papillomavirus L1 capsid protein and human papillomavirus type 16 as prognostic markers in cervical intraepithelial neoplasia 1.
INTRODUCTION The aim of the study was to determine whether human papillomavirus (HPV) L1 capsid protein and the HPV genotype can predict the disease course as prognostic markers for cervical intraepithelial neoplasia 1 (CIN1). METHODS Immunohistochemical staining was performed for HPV L1 capsid protein in 101 women who had been confirmed to have CIN1 by histologic examination and HPV high-ris...
متن کاملPrognostic Value of DNA and mRNA E6/E7 of Human Papillomavirus in the Evolution of Cervical Intraepithelial Neoplasia Grade 2
OBJECTIVE This study aimed at evaluating whether human papillomavirus (HPV) groups and E6/E7 mRNA of HPV 16, 18, 31, 33, and 45 are prognostic of cervical intraepithelial neoplasia (CIN) 2 outcome in women with a cervical smear showing a low-grade squamous intraepithelial lesion (LSIL). METHODS This cohort study included women with biopsy-confirmed CIN 2 who were followed up for 12 months, wi...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2013
ISSN: 1198-743X
DOI: 10.1111/1469-0691.12233